The Onion's interview with Berkeley Breathed is chock full of sharp commentary, of which the following excerpt is not really an example. Well worth reading.

I started as a news photographer at the University Of Texas' Daily Texan. They failed to see the marketing advantage in manipulating news photos (this is pre-digital, remember) to enhance the drama. I recall a dandy front-page photo of a community street preacher, in which I burned a halo floating above his head. I got fired and started writing stories for the campus magazine. I wrote about an unnamed student who secretly released hundreds of baby alligators into nearby Lake Travis, which would have been compelling if I hadn't made it up. Property values around the lake plummeted over $70,000,000 the next week, which brought federal game agents into town. I was arrested, eventually--you think I'm lying again, but I'm not, check the records--and then the death threats and getting kicked out of my apartment complex and I won't bore you with the rest, except to add that some wise sage finally suggested that the cartooning desk might be where I belonged, as I could let my little imagination soar wherever it wanted, and federal agents wouldn't be needed. So I started copying Doonesbury, and you know the rest.